Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression
نویسندگان
چکیده
منابع مشابه
Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression
OBJECTIVE The transcription factor cyclic AMP-responsive element-binding protein H (CREBH, encoded by Creb3l3) is highly expressed in the liver and small intestine. Hepatic CREBH contributes to glucose and triglyceride metabolism by regulating fibroblast growth factor 21 (Fgf21) expression. However, the intestinal CREBH function remains unknown. METHODS To investigate the influence of intesti...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2016
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2016.09.004